Can you provide information on the prevalence and impact of Ehlers-Danlos syndrome (EDS) in the general population?

Ehlers-Danlos syndrome (EDS) is a group of genetic connective tissue disorders that affect the body's ability to produce collagen. It is estimated to affect about 1 in 5,000 people worldwide. EDS can cause a range of symptoms including joint hypermobility, skin hyperextensibility, and tissue fragility. The impact of EDS can vary from mild to severe, affecting a person's quality of life and daily functioning. Early diagnosis and management by healthcare professionals are important in improving outcomes for individuals with EDS.