What is this movie it had an transvestite who took in homeless kids with two runaways who killed him?

The movie you are referring to is likely "The Crying Game." It features a complex narrative involving a transsexual character who becomes involved with a group of homeless children. The plot includes themes of identity, love, and betrayal, culminating in a tragic turn of events. The film is notable for its exploration of gender and sexuality, making it a landmark in cinema.