Which huge land animal has a large head and used to be hunted by Indians?

The huge land animal you are referring to is likely the American bison, also known as the buffalo. These animals have large heads and were historically hunted by Native Americans for their meat, hides, and bones, which were essential for survival. The bison played a crucial role in the culture and economy of many Indigenous tribes in North America. Today, they are a symbol of wildlife conservation efforts.