African cichlids generally should not be kept with neon tetras due to significant differences in temperament and environmental needs. African cichlids are often aggressive and territorial, which can stress or harm the smaller, more peaceful neon tetras. Additionally, cichlids typically thrive in harder, more alkaline water, while neon tetras prefer softer, more acidic conditions. Therefore, it's best to keep these species in separate tanks to ensure their well-being.
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