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combined pattern as the presence of two or more histological variants in the same case. This combined pattern is made up of a predominant subtype, which corresponds to the histological variant with the greatest percentage of tumoral cells, and of a secondary subtype, which corresponds to the subsequent histological variant with the next highest percentage of tumoral cells.

Tumoral histological characteristics included as variables of interest were: thyroid capsule invasion, extra thyroid invasion, vascular invasion, nodal and extra nodal metastasis, tumor size and focality. We are aware about the discrepancy between pathologists on the existence of the thyroid capsule (XX). However, we include it and we used the term because our local guidelines include them, and because the term is still important for a proper TNM classification ().