Why sgpt and sgot are abnormal in dengue patient?

In dengue patients, elevated levels of serum glutamate-pyruvate transaminase (SGPT) and serum glutamate-oxaloacetate transaminase (SGOT) are often indicative of liver involvement, which can occur due to direct viral invasion of liver cells or as a result of immune-mediated liver injury. The release of these enzymes into the bloodstream is a response to liver cell damage, which can be exacerbated by factors such as hypoxia, dehydration, and coagulopathy associated with severe dengue. Monitoring these enzyme levels helps assess the severity of liver impairment and overall disease progression in dengue patients.