Which parts of the Constitution suggest that the framers was to create a strong centralized political system?

The framers of the Constitution aimed to create a strong centralized political system primarily through the Supremacy Clause (Article VI, Clause 2), which establishes that federal law takes precedence over state laws. Additionally, the Necessary and Proper Clause (Article I, Section 8) grants Congress the authority to make laws required for executing its powers, allowing for flexibility and centralization of authority. The establishment of a strong executive branch (Article II) further emphasizes the desire for a unified national leadership. Lastly, the system of federal courts (Article III) reinforces the federal government's power by providing a judiciary that can interpret laws uniformly across states.