How soon can a second dose of adrenaline be administered during an anaphylactic reaction?

In cases of anaphylaxis, a second dose of adrenaline (epinephrine) can be administered if symptoms do not improve within 5 to 15 minutes after the first dose. If the patient's condition remains severe or worsens, a second dose may be given sooner, typically within 5 minutes. It's important to monitor the patient closely and seek emergency medical assistance. Always follow local guidelines and protocols for anaphylaxis management.