How would you adapt Aristophanes' Lysistrata for a modern day audience?

If you mean black-mailing men with sex to get something in return - then yes you "could" do it.

Some men would be swayed but you can forget about them ever loving you - EVER. You would be the most hated thing in their life after what you did.

If you're ok with that - have fun with your sex-strike or should i say "sex- blackmail" :)