Should I start Harley Quinn's revenge on my main save?

If you're a fan of the story and gameplay mechanics in the Harley Quinn's Revenge DLC, it could be a great addition to your main save. The content offers a unique perspective and challenges that enhance the overall experience. However, ensure you're at a suitable level and have completed the main story to fully appreciate the new narrative. Ultimately, it depends on your interest in expanding the game's universe!