How much Bupropion HCL causes fatal overdose?

The lethal dose of bupropion HCL can vary significantly among individuals due to factors such as body weight, tolerance, and concurrent use of other substances. While doses above 400 mg per day are typically associated with an increased risk of seizures, fatal overdoses can occur with doses significantly lower than that, especially if combined with other medications or substances. Reports suggest that doses exceeding 2,000 mg may be life-threatening, but individual susceptibility plays a crucial role. Always consult a healthcare professional for personalized advice and information.