The very, very WORST recreational drugs are industrial chemicals used to create the effect of heroin, under the nickname "Crocodile." The effects are extremely destructive. It literally causes the body to decay, causing tissue to rot away and even resulting in amputation of limbs.
Crystal meth - common among homeless people, is cheap, has more powerful effects than cocaine, and is extremely chemically addictive.
Alcohol, although legal is well known to cause health problems, especially liver damage.
Pharmaceutical pills. Made with good medical intentions but also known to cause liver damage over time.
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