What is the composition of simulated gastric fluid?

Simulated gastric fluid typically consists of a mixture that mimics the acidic environment of the human stomach. It usually contains hydrochloric acid (HCl) to achieve a pH around 1.2 to 3.0, along with pepsin, an enzyme that aids in protein digestion. Sometimes, sodium chloride is added to enhance osmotic balance. This composition is used in laboratory settings to study the dissolution and stability of pharmaceuticals.