How long has Bisquick been required to be refrigerated?

Bisquick has not traditionally required refrigeration. The product is a dry pancake and baking mix that can be stored at room temperature, as long as it is kept in a cool, dry place. However, once opened, it is recommended to keep it tightly sealed to maintain freshness, but refrigeration is not necessary. Always check the packaging for specific storage instructions, as formulations may change.