What anime tv show does a girl rub her high heels up a boys balls?

The scene you're referring to is from the anime "Kagaku na Yatsura" (also known as "Science Fell in Love, So I Tried to Prove It"). It features comedic and romantic elements, with characters engaging in exaggerated situations. This particular moment is meant to be humorous and is typical of the show's over-the-top style.