After calcium ions bind to troponin, a conformational change occurs that moves tropomyosin away from the binding sites on actin filaments. This exposure allows myosin heads to attach to the actin, forming cross-bridges. The myosin heads then pivot, pulling the actin filaments toward the center of the sarcomere, which facilitates muscle contraction. This process is powered by ATP, leading to muscle shortening and force generation.
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