What is a tight junction and what is a desmosome and what is a gap junction?

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2026-05-13 21:25

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Tight junctions are specialized connections between adjacent epithelial cells that create a barrier to prevent the passage of substances between cells, thereby maintaining distinct environments on either side of the tissue. Desmosomes are intercellular junctions that provide mechanical strength by anchoring adjacent cells together, allowing them to withstand stress and tension. Gap junctions are channels that allow direct communication between neighboring cells by enabling the transfer of ions and small molecules, facilitating coordinated cellular activities. Together, these junctions play crucial roles in maintaining tissue integrity and function.

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