Obviously not, if it's meaning and value was lost no one would be interested in it.
google estimates that as of August 2010, there were 129,864,880 books in existence.
Bowkers, the company in the U.S. who issues ISBN numbers has this many stats:
300,000 books were published in the U.S. 2003.
411,422 books were published in the U.S. in 2007.
1,052,803 books were published in the U.S. 2009.
Approximately 3,000,000 books were published in the U.S. in 2011.
Literature includes both eletronic books and those published professonally.
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