What are the best practices for applying tub and tile silicone to ensure a proper seal and long-lasting results?

To apply tub and tile silicone effectively, clean the surface thoroughly, cut the tip of the silicone tube at a 45-degree angle, apply a consistent bead of silicone, smooth it with a wet finger or tool, and let it cure completely before using the area. This will ensure a proper seal and long-lasting results.