Where colesistokinin is produced?

Cholecystokinin (CCK) is primarily produced in the I cells of the duodenum, which is the first segment of the small intestine. It is secreted in response to the presence of fats and proteins in the digestive tract. CCK plays a crucial role in digestion by stimulating the gallbladder to release bile and the pancreas to secrete digestive enzymes. Additionally, it also contributes to the regulation of appetite and satiety.