Can prednisolone be absorbed through the skin?

Prednisolone is not typically absorbed through the skin in significant amounts when applied topically. While some corticosteroids can penetrate the skin and enter the bloodstream, prednisolone is primarily used in oral or injectable forms for systemic effects. Topical formulations containing prednisolone are designed for localized treatment and are not intended for systemic absorption. Always consult a healthcare professional for guidance on medication use.