Has there ever been a woman vice president?

No. The highest office that a woman has been in United States history, was that of Speaker of the House of Representatives. It was held by Nancy Pelosi when the Democrats controlled the House in 2008 to 2010. When she was elected by her fellow House Representatives, it had been the first time that a President (George W. Bush), started a State of the Union Address with Mr. Vice President and Madame Secretary... It was a milestone in U.S. History.