Can sansa e 280 accept mini sd hc cards?

A Sandisk Sansa e200 series, including e280, e270, e260 and e250 will only accept a micro sd card. If the device is a v1, it can only accept a card that is NOT HD. The v2 version will take HD. You can install a third party firmware on the v1 and that will alow you to use micro SDHC cards to 32gb. For more information, go to www.rockbox.org