What enzymes must be present for DNA replication to proceed normally?

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2026-05-04 18:35

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For DNA replication to proceed normally, several key enzymes are required, including DNA helicase, which unwinds the double-stranded DNA, and DNA polymerase, which synthesizes new DNA strands by adding nucleotides complementary to the template strand. Additionally, primase is necessary to synthesize RNA primers, providing a starting point for DNA polymerase. Finally, DNA ligase is essential for joining Okazaki fragments on the lagging strand, ensuring the newly synthesized DNA is continuous.

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