Can you take ambien and Xanax with Benadryl?

Generally, I would not advise it because of the double sedative effect that could occur. Benadryl which is OTC (over the counter) is commonly used as an anti-histamine. Ambien (a prescription) is used specifically for bed-time rest.

However, they can be used together. Senior citizens, people with respiratory issues and the physically handicapped should be monitored from time to time while using these products, especially simultaneously.

- i definitely wouldn't. A friend of mine passed away from it