well idk when it is safe. but the other day my friend took a vicodin while drinking. and kept drinking after wards, not much but a few beers, with a shot of hennessy and redbull, and he wus behaving hyper, his pupils got big but he was okay. he only took the vicodin once its not like its perscribe to him. but later at night, his energy gone done and felt sleepy..... it almost seem as if it were a side affect of a energy drink, first full of energy then tired later.
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