How protein sequence determine protein structure?

Protein sequences, composed of amino acids linked by peptide bonds, dictate the protein's three-dimensional structure through the properties of the individual amino acids and their interactions. The sequence determines how the chain folds into secondary structures like alpha helices and beta sheets, and further into tertiary and quaternary structures due to interactions such as hydrogen bonds, hydrophobic interactions, and ionic bonds. Additionally, the specific order of amino acids influences the protein's stability and function, ultimately determining its role in biological processes.