How would Neville Chamberlain have defended the policy of appeasement?

It was an attempt to avoid war. Nobody wanted to go through all of that death and destruction, yet when an enemy is intent on destroying you, you must fight. In the case of Germany, they were intent on ruling all of Europe and eventually the world. No amount of appeasement would have deterred Hitler. He believed it to be the Aryan right. It's a lesson we should have learned. No amount of appeasement will deter radical Islam. They too are intent on ruling the world.