The germ theory of disease, which proposes that microorganisms are the cause of many diseases, began to take shape in the mid-19th century, largely through the work of scientists like Louis Pasteur and Robert Koch. This theory fundamentally changed medical science and remained the dominant explanation for Infectious Diseases. While it has evolved with advancements in microbiology and genetics, the core principles of germ theory continue to be relevant in modern medicine today. Thus, while it originated over 150 years ago, its impact and relevance persist.
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