How can i describe the effects of a frame-shift mutation?

A frame-shift mutation occurs when nucleotides are added or deleted from a DNA sequence, altering the reading frame of the genetic code. This shift can lead to the production of an entirely different and often nonfunctional protein, as the sequence of amino acids is changed downstream of the mutation. Consequently, frame-shift mutations can result in significant biological consequences, including diseases or developmental disorders, depending on the protein affected. Overall, they disrupt normal cellular function by producing abnormal proteins or prematurely truncating them.