Yeast don't thrive in Diet Coke primarily because it contains artificial sweeteners, such as Aspartame or sucralose, which yeast cannot metabolize for energy like they do with regular sugars. Additionally, the high acidity and carbonation of Diet Coke can create an inhospitable environment for yeast growth. As a result, yeast are unable to ferment Diet Coke effectively, limiting their ability to reproduce and produce carbon dioxide.
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