Can bearded dragons cause skin irriations?

Their claws are sharp, and can leave small scratches, which may irritate. Apart from that, if you have an allergy to the dragon or to its feeder insects, this may irritate your skin when you handle it. Allergies to reptiles are rare, but not unheard of. Allergies to insects are more common.

If you are allergic to the dragon, wear long sleeves and thin gloves when handling the lizard, and have someone else clean the cage, to avoid inhaling the dust from the droppings, and the skin fragments.