Can you take shrooms with anti depressants?

No this is not recommended at all. Shrooms can cause a great deal of anxiety even if you have a very clean and happy experience. Anti-depressants can exacerbate this anxiety to very profound levels. This can cause the user to become extremely paranoid and anxious and lead to a trip to the hospital. If you're going to trip shrooms, don't take the anti-depressants. Also, if you are being prescribed anti-depressants you should steer clear of hallucinogenics because they temporarily alter your brain chemistry and can lead to depression or the "blues" for a few days after the trip (from first hand experience multiple times). If you're already depressed it will only be worse. Please be nice to your brain. (From an experienced tripper and microbiology student)