What are the effects of the league of nations?

When the US refused to join the League of Nations this weakened the League of Nations severely. The US government relied on check and balance system as well at this time the US was going through the Great Depression. The League of Nations tried to impose an economical sanction against Italy. When the US found out about it they decided to trade everything Italy had to trade. Once the other countries found out about the decision of the US they realized that the League of Nations was ineffective.