What are two serious side affects of gentamycin and tobramycin?

Two serious side effects of gentamicin and tobramycin are nephrotoxicity, which can lead to kidney damage, and ototoxicity, which may result in hearing loss or balance issues. These antibiotics can cause cumulative toxicity, especially in patients with pre-existing kidney conditions or those receiving high doses. Regular monitoring of kidney function and hearing is essential during treatment to mitigate these risks.