How do you remove a 100 amp fuse?

Assuming the fuse is the type that is pressed into it's contacts, and assuming the fuse is de-energized when the disconnect is open (off), I usually place a screw driver behind the fuse on one end or the other, pull it out until I can get hold of it, and pull it out completely. As a matter of standard practice you want to wear leather gloves and treat it like it is hot (energized) until it is removed. If it is big enough you can simplify this procedure by just grabbing the fuse with one hand and pull. It should be extremely tight so be careful not to throw the fuse or your hand into something else that is energized.