What are side affects from metadone and seroquel being took together?

Swim has abused these drugs recently, Swim has found that taking Seroquel in combination with Valium (which swim has much more experience with) produced a profound high with marked disorientation, confusion, and lack of motor control. The doses swim used were 25-40MG of Valium coupled with 75-150mg of Seroquel. Valium alone does not produce a pronounced high in Swim. Swim found the Seroquel to be particularly debilitating and a dangerous additive for a mix of Valium,Xanax, and cannabis. But regarding your problem, Swim thinks that Seroquel tolerance plays a major role in the equation, along with dosage. If you have Seroquel tolerance already, Swim is certain that an individual with tolerance would react much differently to the combination, and not suffer such debilitating effects. Otherwise be careful not to over do it or you may get extremely groggy, confused, frustrated, and generally unable to function in a way that Swim found almost disturbing.