Can you take Tylenol and antibiotics together?

Yes, you can. The popular brand of OTC pain reliever, Excedrin, is actually just that - a combination of these two drugs, plus the amount of caffeine equal to one cup of coffee.

For adults, if the pain is severe, you can take two aspirin and two acetaminophen at the same time, then alternate the two drugs every two hours afterwards. For example, after taking two of the aspirin and two acetaminophen, wait two hours, then take two aspirin OR two acetaminophen, then in two more hours, take two of the other. Do NOT continue this for more than one day without your doctors approval.