What are negative effect of microorganisms in in human life?

Microorganisms can have several negative effects on human life, primarily through their role in causing diseases. Pathogenic bacteria, viruses, and fungi can lead to infections that result in illnesses ranging from mild to severe, sometimes even fatal. Additionally, some microorganisms can produce toxins that harm human health or contaminate food and water supplies, leading to outbreaks and public health concerns. Furthermore, the disruption of beneficial microbial communities in the human body can contribute to conditions like obesity and autoimmune disorders.