In the early 1600s which issue regarding contact between Europeans and the Japanese was a primary area of concern for the Tokugawa regime?

In the early 1600s, the primary concern of the Tokugawa regime regarding contact between Europeans and the Japanese was the potential for Christianity to undermine Japanese social order and loyalty to the shogunate. The influx of European missionaries and the conversion of many Japanese to Christianity raised fears of foreign influence and the disruption of traditional values. This led to the eventual persecution of Christians and the implementation of strict policies to limit foreign interactions, culminating in Japan's sakoku (closed country) policy.