Ask a trained vet.
(From a vet); if your vet has prescribed it, it IS possible, but not reccomended unless absolutely necessary. The antibiotic will enter the milk and get in to the puppies - depending on how much they drink this could potentially be harmful to them. If the female needs penicillin (e.g. for a womb or mammary infection) we sometimes prescribe penicillin, but monitor carefully. If possible it is best to hand rear the puppies while the mother receives medication.
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