always take thyroid meds on an empty stomach. In the morning take the thyroid and wait an hour to eat or drink anything. Take meds after this hour and try to take vitamins much later. If you take the thyroid at night, you must go three hours of nothing to empty your stomach and then the one hour again. Best to take it in the morning. I set my alarm, take it with just enough water to swallow and go back to sleep.
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