Antihistamines limit the gastric secretion of gastric acid by blocking histamine H2 receptors in the stomach lining. Histamine stimulates the parietal cells to secrete hydrochloric acid, crucial for digestion. By inhibiting this action, antihistamines can reduce overall gastric acidity, which may be beneficial in conditions like gastritis or peptic ulcers. However, they are primarily used for allergy relief rather than as a primary treatment for gastric acid issues.
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