No, the Missouri Compromise did not end slavery in the South. Instead, it was an attempt to maintain a balance between free and slave states by admitting Missouri as a slave state and Maine as a free state. The compromise established a line (the 36°30' parallel) to determine the future status of slavery in territories north and south of that line, but it ultimately did not resolve the underlying tensions over slavery, which continued to escalate leading to the Civil War.
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