How do you address pastor and wife?

The Reverend (first name) and Mrs. (first name) Surname

Note that the title "The Reverend" takes the first name not the surname. Thus, if John Smith is ordained his correct title is not "The Reverend Smith" but "The Reverend John Smith". Note also that a definite article is required: "The Reverend", never simply "Reverend".

Just Reverend is for conversation only when speaking to the Reverend face to face.