The 2001 Cadillac DeVille typically requires about 2.5 to 3.0 pounds of R-134a refrigerant for a complete recharge of the air conditioning system. It's important to check the specific service manual for the vehicle or any labels under the hood for the exact specifications, as variations may exist. Always ensure that the system is properly evacuated and vacuumed before recharging with refrigerant.
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