How does chickenpox affect someone without a spleen?

Chickenpox can be more severe in individuals without a spleen, as the spleen plays a crucial role in the immune system by filtering blood and fighting infections. Without this organ, the risk of complications, such as pneumonia or severe skin infections, increases. Additionally, individuals without a spleen may not respond as effectively to vaccines, making them more susceptible to viral infections like chickenpox. It is important for such individuals to seek medical attention promptly if exposed to the virus.