Does Fentanyl cause itching post op?

Yes, fentanyl can cause itching as a side effect, particularly in a postoperative setting. This itching is often due to the drug's effect on opioid receptors, which can trigger histamine release or other mechanisms. While not everyone experiences this side effect, it is relatively common with opioids. If itching occurs, it can usually be managed with antihistamines or by adjusting the pain management regimen.