506 miles taking this route:
- Follow the New York State THRUWAY (toll road) EAST on I-90 from Buffalo across to Massachusetts, where I-90 continues as the MASSACHUSETTS TURNPIKE (marked by a BLACK PILGRIM HAT) (toll road), towards Boston, at EXIT 21A off the THRUWAY.
- Continue EAST on I-90 MASSACHUSETTS TURNPIKE (toll) EAST across to I-495 to N.H. - MAINE at EXIT 11; follow signs on the exit ramp to I-495 NORTH to N.H. - MAINE.
- Take I-495 NORTH up to I-95 NORTH, towards N.H. and Maine.
- Take I-95 NORTH into New Hampshire, where I-95 continues as the NEW HAMPSHIRE TURNPIKE, which is a TOLL ROAD.
- Take I-95 NEW HAMPSHIRE TURNPIKE (toll) NORTH to the SPALDING TURNPIKE (signed with a BLUE DOT)/U.S. 4, at LEFT EXIT 4.
- Take the SPALDING TURNPIKE - NORTH to U.S. 4 WEST to DURHAM at EXIT 6W.
- Continue on U.S. 4 WEST to DURHAM.
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