To change the radiator on a 2001 Lexus IS300, start by ensuring the engine is cool and disconnect the negative battery terminal. Drain the coolant by removing the drain plug at the bottom of the radiator and disconnect the upper and lower radiator hoses. Then, remove the mounting bolts and any attached components, such as the fan shroud, before lifting the old radiator out. Install the new radiator by reversing the process, ensuring all connections are secure, and refill the cooling system with the appropriate coolant.
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